Pathology and Current Treatment of the Alzheimers Disease Essay

Pathology and Current Treatment of the Alzheimers DiseaseIntroductionOne of the closely feared aspects of aging is the deterioration of the memory and cognitive function (dementia) that occurs among the elderly with increase frequency with advancing years. A significant proportion of otherwise florid elderly persons show a significant decline in kind function later in life. It has been estimated that 10% of the population over the geezerhood of 65 suffers from mild to moderate dementia and 4-5% suffer from severe dementia. The incidence of severe dementia rises from less than 1% at ages 65 to 70 to over 15% by age 85 (Terry and Katzman, 1983). In the coupled States alone, Alzheimers disease (AD), which is the major ca delectation of senile dementia, afflicts several gazillion people, and with the change magnitude longevity of the population, the number of such patient ofs requiring complete and continuous institutional care will rise to epidemic proportions. This paper will tackle to describe the Alzheimers Disease condition, both behaviorally and neuropathologically, and then look at conventional and current methods of treatment for patients of Alzheimers Disease.The onset of senile dementia is characterized by increasing impairment of memory of recent events such as what a patient had for breakfast an hour earlier, though a detailed recall of the far-flung past may be essentially intact. Inevitably, the patients lose their cognitive abilities, that is, their abilities to read, write, calculate, and use language appropriately they cannot feed or dress themselves, they do not recognize their suffer families, they get lost when only a presently distance from home, and ultimately do not even know their own names (R. Perry et al., 2000, C.J.A. Mouli... ...minimal and mild) Alzheimers Disease relationship to episodic and semantic memory impairment, Neuropsychologia, 383, 2000, p. 252-271Prasad, K.N., Hovland, A.R., Cole, W.C., Prasad, K.C., Nahreini, P., Edwards-Prasad, J., Andreatta, C.P. Multiple antioxidants in the prevention and treatment of Alzheimers Disease Analysis of biochemical rationale, Clinical Neuropharmacology, 231, 2000, p. 2-13Roses, A.D. Apolipoprotein E affects the rate of Alzheimers Disease expression b -amyloid burden is a secondary consequence dependent on apoE genotype and duration of disease, J. Neuropathol. Exp. Neurol, 53, 1994, p. 429-437Terry, R.D., Katzman, R. Senile dementia of the Alzheimers type, Ann. Neurol., 14, 1983, p. 497-506van Leuven, F. Single and three-fold transgenic mice as models for Alzheimers Disease, Progress in Neurobiology, 613, 2000, p. 305-312